Firefighters are currently in attendance at a fire on Sankey Valley Industrial Estate in Newton-le-Willows, St Helens.
20 fire engines, two combined platform ladders and high volume pumps are in attendance. This has been declared a major incident.
A spokesperson from the Merseyside Fire And Rescue Service said:
"Crews were alerted at 11.08am and on scene at 11.15am.
"On arrival crews found a large fire approximately 30m x 15m. Firefighters wearing breathing apparatus are currently tackling the fire using a main branch.
"A large volume of smoke is being produced by the fire. Nearby businesses and residents should keep windows and doors closed. Anyone with existing medical conditions should keep medicine nearby and call NHS 111 if ill effects occur.
"The incident is ongoing.
"Please avoid the area and continue to follow previous advice of keeping windows and doors closed."